Micron Spherical Silica Gel Powder for Cosmetics Additive and Column Chromatography
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The role of silica gel in chromatography


Silica gel for chromatography is a porous material, with the cross chain structure of siloxane in the molecule, and there are many silanol groups on the particle surface. The strength of silica gel adsorption is related to the content of silanol groups. The silanol groups can absorb water through the formation of hydrogen bonds, so the adsorption capacity of silica gel decreases with the increase of the absorbed water.

If the water absorption capacity exceeds 17%, the adsorption capacity is extremely weak and cannot be used as an adsorbent, but it can be used as a supporting agent in the distribution chromatography to activate the silica gel. When the silica gel is heated to 100~110 ° C, the water absorbed by the hydrogen bond on the silica gel surface can be removed.

When the temperature rises to 500 ° C, the silanol group on the silica gel surface can also be dehydrated and condensed into siloxane bonds, so the activation of silica gel should not be carried out at a higher temperature (generally, a small amount of bound water is lost above 170 ° C).

Silica gel is an acidic adsorbent, which is suitable for chromatography of neutral or acidic components. At the same time, silica gel is a weak acidic cation exchanger. The silanol group on its surface can release weak acidic hydrogen ions. When encountering strong alkaline compounds, it can adsorb alkaline compounds due to ion exchange reaction.

Introduction to relevant manufacturers:

Dongying Yiming New Materials Co., Ltd. is a professional manufacturer of chromatographic separation materials and technical service provider, mainly engaged in column chromatography silica gel, thin layer chromatography silica gel plate, FNG water resistant silica gel, etc.

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