Micron Spherical Silica Gel Powder for Cosmetics Additive and Column Chromatography
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Selection of chromatographic packing


1. Silica gel matrix


Silica gel matrix is the most common matrix among chromatographic packings. In addition to its high strength, it also provides a surface that can be used to bond various ligands through mature silylation technology to make packings for reverse phase, ion exchange, hydrophobic interaction, hydrophilicity or molecular exclusion chromatography. Silica gel matrix packings are applicable to a wide range of polar and nonpolar solvents. The disadvantage is that they are usually unstable in alkaline watersoluble mobile phases, The recommended pH range for routine analysis of silica based fillers is 2~8.


2. Alumina matrix


The aluminum oxide matrix has the same good physical properties as silica gel, and can also withstand a large pH range. It is also rigid and will not shrink or expand in the solvent. However, unlike silica gel, the aluminum oxide bonding phase is unstable in the aqueous mobile phase. However, aluminum oxide bonding phase that is stable in the aqueous phase has emerged and shows excellent pH stability.


3. Polymer filler


Polymer fillers include polystyrene divinylbenzene copolymer, polydivinylbenzene pyrrolidone copolymer, methyl methacrylate and its ionization products. These polymer fillers have excellent physical and chemical properties.